Endocrine Abstracts

Introduction: Ectopic parathyroid adenomas are detected 16% of patients operated for primary hyperparathyroidism and 22% of them may be located in the anterosuperior mediastinal region. Herein we present a rare case of primary hyperparathyroidism with severe long-term elevated parathormone (PTH) levels due to ectopic parathyroid adenoma in mediastinal region that was successfully treated by using video-assisted thoracic surgery (VATS).Case report: A 38-y...

Objective: Hyperprolactinemia is the most common abnormality of the hypothalamic–pituitary axis. In the majority of patients with hyperprolactinemia monomeric prolactin (monoPRL) namely PRL with a molecular weight of 23 kDa predominates. But, in some patients with hyperprolactinemia high molecular weight forms of PRL namely macroprolactin (macroPRL) is detected. We aimed to investigate the clinic and radiologic features associated with the macroPRL....

Introduction: Complementary and alternative medicine (CAM) is a group of diverse medical and health care systems, practices, and products that are not presently considered to be part of conventional medicine. For most of CAM, there are key questions that are yet to be answered through well-designed scientific studies. Obesity is one of the chronic health disorders which is difficult to deal and most of the obese patients are unable to lose or keep weight with diet, exercise or...

Aim: We aimed to investigate the possible relationship between HDL cholesterol subclasses and carotid intima media thickness (CIMT) in patients with type 1 diabetes mellitus (DM).Material and methods: Sixty-two (female/male: 33/29, mean age: 33.3±8.5 years) patients with type 1 DM at least 5 years and 20 (female/male: 10/10, mean age: 30.4±5.6 years) healthy controls were included in the study. After physical examination and anthropometric meas...

Aim: Overt/subclinic hypothyroidism and hyperthyroidism are known to be associated with cardiovascular risks. There have been no studies evaluating the relationship between nodule presence and arterial stiffness in individuals with euthyroid nodular goitre. Our aim in this study is to demonstrate whether nodule presence and nodule stiffness affect arterial stiffness in individuals with euthyroid nodular goitre by using pulse wave analysis (PWA).Materials...

IntroductionAdrenal abnormalities can be detected incidentally during the imaging performed for malignancies. These abnormalities may include adrenal pathological conditions independent of primary malignancies. Pheochromocytomas detected as part of some familial syndromes are often bilateral.In this report, we present a case of isolated sporadic bilateral pheochromocytoma that was incidentally detected during malignancy workup and staging, which is a rar...

IntroductionMEN 2A is an autosomal dominant disease, a familial syndrome with a mutation at RET proto-oncogene. %25 of medullary thyroid carcinoma (MTC) is a part of MEN 2A. Herein, we presented a patient with MEN 2A who was found to be heterozygos for RET mutation cause of the association of MTC and papillary thyroid carcinoma (PTC) is very rare.Case63 year old patient was admitted to the endocrinology clini...

IntroductionMucopolysaccharidosis type 4A (Morquio 4A) is an autosomal recessive lysosomal storage disease caused by a mutation in the gene encoding galactosamine 6 sulphatase (GALNS). It’s main clinical features include short stature, skeletal dysplasia, cloudy cornea, hearing loss and dental anomalies. Herein, a case of Morquio 4A, a rare cause of short stature is presented.Case reportA 41 year old fem...

IntroductionImmunological side effects related with use of immune checkpoint inhibitors (ICIs) are named as immune-related adverse events (irAEs). irAEs include clinical pictures such as autoimmune thyroiditis, hypophysitis, primary adrenal insufficiency and autoimmune diabetes mellitus. Nivolumab is an anti-PD-1 (anti-programmed cell death-1) monoclonal antibody approved for the treatment of malignant melanoma, advanced non-small cell lung cancer and ad...

Background: Atypical parathyroid adenoma (APA) is a rare disease that can be challenging to distinguish from benign parathyroid adenoma. APA shows some laboratory and histopathological features with parathyroid cancer. This study attempts to compare clinical, laboratory, radiologic and histopathological characteristics in APA and parathyroid adenoma (PA).Methods: This was a retrospective study was based on the database of eighty-two subjects who underwen...